Here's one McGuffin I recently found in the wild on The Penguins of Madagascar (Season 2, It's About Time):
Kowalski: (Sighs) Oh Skipper, I don't think you're seeing the big picture here. With the Chronotron we'll be able to visit any period in history!
After taking a sip, Skipper throws his cup of joe to the side, and punches his open hand while talking.Skipper: Outstanding! Finally those hippies can be stopped! C'mon Rico!
Skipper and Rico slowly advance towards the Chrono-tron.Rico: (Angrily) Hippies!Kowalski: Hold on Skipper, the Chronotron needs just one more thing before it's fully functional. Five ounces of Macguffium-239. Fortunately I know where to find some right here in midtown.Kowalski pulls out a City Map and points to the center of it.